After playing an uncredited small role in Zee TV's Maayka in 2006, Uttam was set to star as the title character in Star Plus's Kasturi and make her debut in a leading character, but later Shubhangi Atre replaced her.[8]
In 2009, Uttam was cast in Star Plus's longest-running Indian daily soap, Yeh Rishta Kya Kehlata Hai as Nandini Singhania which she eventually quit in 2016.[citation needed]
Along with her role of Nandini, she portrayed Meethi in Life OK's Ek Boond Ishq in 2013.[11]
In 2018, she returned to Yeh Rishta Kya Kehlata Hai, but finally confirmed her exit from it in 2019.[14]
The following year, she appeared in the television series Aghori via Zee TV, portraying Priya.[15]
Film career
Nidhi ventured into films with Suniel Shetty starrer Nanha Einstein in 2017.[16]
She appeared in Anubhav Sinha's drama, Thappad, starring Taapsee Pannu as a caring housewife who wants justice against domestic violence, when her husband slaps her unreasonably. Thappad was moderately profitable at the box office earning ₹440 million (US$5.1 million) against its ₹250 million (US$2.9 million).[17]