Nekane made her debut for Athletic in a 4–0 win over ŽNK Krka in the 2007–08 UEFA Women's Cup a few days before her 16th birthday – she found the net in the match, and as of 2023 remained the club's youngest player and goalscorer.[1] She was the third top scorer of the 2010–11 season with 24 goals.[2]
Nekane made a recovery from injury, although her contribution reduced over subsequent seasons. She left Athletic and ended her playing career in 2023, aged 31,[4] having scored total of 162 goals in 381 appearances for the club (second and fourth respectively in their historical rankings).[5][6]