The road opened gradually in 1978 after more than two years of works. The Murgia bypass was opened in mid-June, followed a few weeks later by the stretch from Vitoria-Gasteiz to Arangiz.[4] The Letona-Zarate stretch was opened partially (only one of the carriageways) on 22 August, while the Arangiz-Zarate stretch followed in early September.[5] On 14 October the last remaining section of the road was inaugurated, with the opening of the second Aiurdin tunnel.[6]
On 3 June 2009, the interchange with the new AP-1 motorway at Etxabarri Ibiña opened.[7] Traffic from the AP-1 towards the A-1 motorway uses the N-622 from Etxabarri Ibiña to the cloverleaf interchange with the A-1 near Vitoria-Gasteiz. As a result, that stretch suffers from recurrent traffic jams, particularly in the summer.[8] In 2022, a study to improve the traffic flow in the area was announced.[9]