The book does not have a particular plot. It is designed with numerous blank spaces intended to be filled in by the reader (mostly written, with a few illustrations) with various pieces of information specific to themselves; hence the title, My Book About Me, and the author being listed as "Me, Myself" listing "some help" from Seuss and McKie. The completed book ends up containing a sort of "profile" of the reader. The book is similar to Oh, the Places I'll Go!, a book published under the Seuss name that was inspired by Oh, the Places You'll Go!.
