Murder on the Eurasia Express is an interactive movie and adventure game presented entirely with live-action full motion video. The player takes on the role of a private detective invited by an all-girls private school to join their trip on the Eurasia Express train line. As soon as the train departs from Shanghai, a man on the train is murdered. The player is tasked with investigating and solving the murder across 2 real-time hours. The player must use the D-pad to direct the character through the main hallway and into the various rooms. In each room, the player can speak with the school girls and other passengers to inquire about circumstances surrounding the murder using a dialogue choice box. Through the investigation, the player will collect items and memos which they can view on separate screens. The player also a pocket watch to see how much time is left for their investigation.