Unlike the first film, MVP Entertainment was not involved the film. This is also the last film appearance of comedian German Moreno, who died in a cardiac arrest in Quezon City, Diliman on January 8, 2016, aged 82.[6]
The film begins with the ending scene from the first movie, where Albert Macapagal, Isaac Estrada, Aristotle Ramos, Mozart Twister Aquino, and Michael Angelo Marcos graduate from high school. Albert narrates that they had no idea there would be a sequel and that they only discovered their dreams after finishing college.
Albert aspired to be a lawyer but quit law school due to pressure. He became a hopia salesman in Binondo, got married, and had a child named Marcus (Macoy).
Isaac aspired to enter showbiz but never received callbacks. He ended up working as security personnel at showbiz events, got married, and had a son named Fidel.
Aristotle aspired to be a chef but was repeatedly fired from five-star hotels and restaurants due to his mistakes. He decided to open a bakery, got married, and had a daughter named Gloria.
Mozart aspired to compete in bodybuilding competitions but ended up working in a local gym, where he frequently got into trouble due to being accident-prone. When his mother won a lottery jackpot, he suggested using the money to open a fitness gym. He also got married and had a daughter named Korina (Cory).
Michael Angelo suffered severe facial burns after mistakenly pouring kerosene on their barbecue grill and needed reconstructive plastic surgery. Post-surgery, his new face resembled Matteo Guidicelli's instead of his original face (Mart Escudero). The doctor remarked that his new face could attract girlfriends, including Sarah Geronimo. However, Michael Angelo fell in love with Filomena, Aristotle's aunt.
Despite Albert, Isaac, Aris, Mozart, and Michael Angelo being known for their foolishness, their children are quite the opposite.
Macoy, Gloria, Fidel, and Cory devised a plan to avoid embarrassment caused by their fathers. During their school's recognition ceremony, the fathers, known collectively as the Moron 5, noticed other men being called on stage as the children's fathers. The children were eventually caught red-handed by their parents, having paid the men to pose as their fathers.
One night, during a drinking session, the group witnessed a bright light falling from the sky, which was actually from an airplane struck by lightning. Albert, however, believed it came from space and had superhuman powers. When they placed their hands on the so-called "power source," they were struck by lightning. Convinced they had gained superpowers, they decided to use their abilities to help others. They rebranded themselves from the usual Moron 5 to M5, with Albert as M1, Isaac as M2, Aristotle as M3, Mozart as M4, and Michael Angelo as M5.
The M5's archnemesis, Becky Pamintuan, escapes from a mental facility and plans her revenge on them. Learning about M5, she decides to locate their hideout and seize their power source. After clashing with a terrorist group led by Abdul Ado Remi, Becky and her cohorts abduct the M5's families. She calls Albert, informing him that she has both their families and their "power source."
When the M5 arrived at their hideout, they found Becky holding their families hostage. She demanded they activate the power source in exchange for their freedom. Unbeknownst to the M5, Becky had a remote control capable of shaking the ground. A TV monitor then revealed that they did not have any superpowers and the power source was a hoax. Distraught by this revelation, Becky was taken back to the mental hospital.
During another recognition ceremony, Macoy declared that the ones truly deserving of recognition were their fathers.
