Moose Jaw—Lake Centre was a federal electoral district in Saskatchewan, Canada, that was represented in the House of Commons of Canada from 1953 to 1968 and from 1988 to 1997.

This riding was created in 1953 from parts of Lake Centre, Moose Jaw, Qu'Appelle, and Rosthern ridings

It was abolished in 1966 when it was redistributed into Moose Jaw, Regina East and Regina—Lake Centre ridings.

It was re-created in 1987 from parts of Assiniboia, Humboldt—Lake Centre and Moose Jaw ridings.

The electoral district was abolished in 1996 when it was redistributed into Blackstrap, Cypress Hills—Grasslands, Palliser and Regina—Arm River ridings.

This riding has elected the following members of Parliament:

• List of Canadian federal electoral districts
• Historical federal electoral districts of Canada

• Riding history for Moose Jaw—Lake Centre (1952–1966) from the Library of Parliament
• Riding history for Moose Jaw—Lake Centre (1987–1996) from the Library of Parliament