Diagnostic questionnaire to measure the severity of depressive episodes
Medical diagnostic method
Montgomery–Åsberg Depression Rating Scale
Purpose
severity of depression
The Montgomery–Åsberg Depression Rating Scale (MADRS) is a ten-item[1]diagnostic questionnaire which mental health professionals use to measure the severity of depressive episodes in patients with mood disorders. It was designed in 1979 by British and Swedish researchers (Stuart Montgomery and Marie Åsberg) as an adjunct to the Hamilton Rating Scale for Depression (HAMD) which would be more sensitive to the changes brought on by antidepressants and other forms of treatment than the Hamilton Scale was.[2] There is, however, a high degree of statistical correlation between scores on the two measures.[3]
Interpretation
The questionnaire includes questions on ten symptoms:
Apparent sadness
Reported sadness
Inner tension
Reduced sleep
Reduced appetite
Concentration difficulties
Lassitude
Inability to feel
Pessimistic thoughts
Suicidal thoughts
Each item yields a score of 0 to 6; the overall score thus ranges from 0 to 60.[4]
Higher MADRS score indicates more severe depression.
Usual cutoff points are:
A self-rating version of this scale (MADRS-S) is often used in clinical practice and correlates reasonably well with expert ratings.[6] The MADRS-S instrument has nine questions, with an overall score ranging from 0 to 54 points.[7]
^Montgomery SA, Asberg M (April 1979). "A new depression scale designed to be sensitive to change". British Journal of Psychiatry. 134 (4): 382–89. doi:10.1192/bjp.134.4.382. PMID444788. S2CID22246215.
^Cunningham, JL; et al. (2011). "Agreement between physicians' and patients' ratings on the Montgomery Åsberg Depression Rating Scale". Journal of Affective Disorders. 135 (1–3): 148–53. doi:10.1016/j.jad.2011.07.005. PMID21856017.
^Svanborg, P; Åsberg, M (2001). "A comparison between the Beck Depression Inventory (BDI) and the self-rating version of the Montgomery Åsberg Depression Rating Scale (MADRS)". Journal of Affective Disorders. 64 (2–3): 203–216. doi:10.1016/S0165-0327(00)00242-1. PMID11313087.