The structure was built in 1959 as an apartment building. It was later renovated and reopened in 1985 as the Le Mondrian by the L'Ermitage Hotel Group. The outside of Le Mondrian featured a commissioned work by Yaacov Agam entitled L'Hommage a Mondrian which covered the hotel's 9 story exterior.
In April 2011, Morgans Hotel Group reached a deal to sell the Mondrian Los Angeles to Pebblebrook Hotel Trust for $137 million. Morgans Hotel Group will continue to manage the hotel under a 20-year agreement.[3]
In November 2020, all of SBE Entertainment Group's hotel holdings were sold to Accor, after it already acquired a 50% stake in 2018.[5] As of 2020, the Mondrian brand of hotels, including its flagship in Los Angeles, is being managed by Accor's lifestyle subsidiary Ennismore.[6]
The lyrics to Dr. Dooom and Jacky Jasper's song "Neighbours Next Door", from First Come, First Served (1999), state: "Lookin' out your Mondrian Hotel window, like Elvis Presley coming down the elevator."
Several episodes of the HBO series Entourage were filmed on-location at the Mondrian.[citation needed]
In the third installment of the Family Guy'sStar Wars parody, "Episode VI It's a trap", about 16:11 into the episode, the character played by Angela thanks her audience for meeting her "in the lobby of the Mondrian", drawing a comparison between the Mondrian Miami lobby's futuristic design and the interior of a Star Wars spaceship.