Mona Island is a natural reserve and there are no permanent inhabitants. Rangers from the Department of Natural and Environmental Resources rotate residence on the island to manage visitors and take part in research projects.
The runway parallels the island's southwest shore. Approach and departures are over the water. An overrun to the northwest will hit some coral rock outcroppings.
The Mayaguez VOR/DME (Ident: MAZ) is located 45.8 nautical miles (52.7 mi) east-northeast of Mona Airport. The Punta Cana VOR/DME (Ident: PNA) is located in the Dominican Republic 39.2 nautical miles (45.1 mi) northwest of the airstrip.[3][4]