Route 58 is a highway in western Missouri. Its eastern terminus is at U.S. Route 50 west of Warrensburg; its western terminus is at Route D west of Belton, Missouri. It is one of only a very few highways to end at a state supplemental route.
Route 58 is one of the original 1922 state highways. Its eastern terminus was at Route 13 in Warrensburg, and its western terminus was at Route 1 (now Route 291) north of Harrisonville. In the 1950s, Route 58 had a spur connecting it with north US 71.