Gandolfi was born in Melrose, Massachusetts. He taught himself guitar as a child, studied for a year at the Berklee College of Music, and then entered NEC, where he earned his bachelor's and master's degrees.[1]
His The Garden of Cosmic Speculation was inspired by Charles Jencks' garden in Scotland that incorporates modern physics into its design. It was nominated for Best Contemporary Classical Composition at the 2009 Grammy Awards, His Trivia, written for the Weilerstein Trio, uses Richard Wolfson's book Simply Einstein as a source.