The highway is briefly interrupted from El Encinal to Soto la Marina in Tamaulipas just north of Tampico. The highway goes through Tampico south, interrupted briefly from Cerro Azul to Potrero del Llano, to the city of Poza Rica. It continues south from there through Veracruz and Coatzacoalcos. From there it goes east into Villahermosa, north through Campeche into Mérida, and finally east into Cancún.
Highway 180 connects at the Mexico–U.S. border with U.S. Route 83, one of the longest north–south U.S. Highways in the United States at 3,034 km (1,885 mi). Federal Highway 180 also connects with Interstate 69E/U.S. Route 77 at the border. U.S. Route 83 (along with Interstate 69E/U.S. Route 77) starts the northern terminus of Highway 180 in Brownsville, Texas, at the Veterans International Bridge on the border. After crossing the bridge into the United States, Federal Highway 180 continues as U.S. Route 83 in Brownsville which then runs northward to the U.S. highway's northern terminus, north of Westhope, North Dakota, at the Canada–United States border. From here, the highway continues further as Manitoba Highway 83 until it ends at Swan River, Manitoba. In total, the three highways total 5,691 km (3,536 mi) in length.
Image gallery
Heading towards Cancun from Mérida
Carretera Federal 180 looking northbound near Gutiérrez Zamora.