María de Toledo or María Álvarez de Toledo or María Álvarez de Toledo y Rojas (1490 – 11 May 1549) was a Spanish noblewoman and Vicereine and regent of the Spanish Colony of Santo Domingo on Hispaniola, present day Dominican Republic. She was the most powerful and highest-ranking noble in America in the 16th century and a defender of the liberties of the indigenous people in the Hispaniola.[1]
During the absence of her husband from 1514 until 1520, she was left in charge of the colony along with Jerónimo de Agüero. In 1523, when Diego was recalled a second time, she was named virreina. She was then expecting their eighth child.[2]
Cristóbal Colón de Toledo (c. 1510 – 1571), married firstly to María Leonor Lerma de Zuazo, without issue; married secondly to Ana de Pravia, and had one son (Diego Colon y Pravia [c. 1551 - Jan 27, 1578]) and one daughter (Francisca Colon y Pravia, [c. 1552 - April 1616]; and married thirdly to María Magadalena de Guzmán y Anaya, and had:
Diego Colón de Toledo, father of Diego the 4th Admiral of the Indies.
Francisca Colón de Toledo y Pravia (c. 1550 – April, 1616), married Diego de Ortegón (c. 1550 –), and had four children: Guiomar de Ortegon y Colon [d. 1621]; Jacoba de Oretgon y Colon [d. 1618]; Ana de Ortegon y Colon; and Josefa de Ortegon y Colon[3]
María Colón de Toledo y Guzmán (c. 1550 –), married to Luis de Avila, and had:
Cristóbal de Avila y Colón (1579 –), unmarried and without issue
Luis de Avila y Colón (1582-1633), married Maria de Rojas-Guzman Grajeda, without issue; married secondly to Francisca de Sandoval and had one son Cristobal
Juan Colón Dávila (-1622)
Bernardino Dávila y Colón (-1633)
Maria de Avila y Colón (1592-), married Alonso de Guzman Grajeda and had one daughter (Mayor de Grajeda y Avila [c.1611-]
Juana Colón de Toledo (died c. 1592), married her cousin Luis de La Cueva y Toledo; their only child was María Colón de la Cueva (c. 1548-c.1600) who claimed the duchy of Veragua and died in New Spain (México).[4]
Isabel Colón de Toledo (c. 1515 –), married Dom Jorge Alberto de Portugal y Melo (1470 –), 1st Count of Gelves (who married secondly; his 1st marriage to Dona Guiomar de Ataíde remained childless), son of Dom Álvaro de Bragança, Lord of Tentúgal, Póvoa, Buarcos and Cadaval and Chancellor-Major of the Realm of Portugal. Their grandson, D. Nuno Alvares Pereira Colón y Portugal, Duke of Veragua and Admiral of the Indies became regent of the Kingdom of Portugal from 1621 until his death.
Maura, Juan Francisco; Maura, Hernando (2005). Españolas de ultramar en la historia y en la literatura. Valencia: Universitat de València, Colección Parnaseo, 1. ISBN8437062454.
Vega, Carlos B. (2003). Conquistadoras: mujeres heroicas de la conquista de América. Jefferson, NC (EEUU): McFarland & Co.. ISBN9780786416011.