MICAL1
Protein-coding gene in the species Homo sapiens
NEDD9-interacting protein with calponin homology and LIM domains is a protein that in humans is encoded by the MICAL1 gene .[ 4] [ 5]
Interactions
MICAL1 has been shown to interact with NEDD9 [ 4] RAB1A .[ 6]
References
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019823 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ a b Suzuki T, Nakamoto T, Ogawa S, Seo S, Matsumura T, Tachibana K, Morimoto C, Hirai H (Apr 2002). "MICAL, a novel CasL interacting molecule, associates with vimentin" . J Biol Chem . 277 (17): 14933–41. doi :10.1074/jbc.M111842200 PMID 11827972 . ^ "Entrez Gene: MICAL1 microtubule associated monoxygenase, calponin and LIM domain containing 1" .^ Weide, Thomas; Teuber Julia; Bayer Michael; Barnekow Angelika (Jun 2003). "MICAL-1 isoforms, novel rab1 interacting proteins". Biochem. Biophys. Res. Commun . 306 (1). United States: 79–86. doi :10.1016/S0006-291X(03)00918-5 . ISSN 0006-291X . PMID 12788069 .
Further reading
Iwata S, Ohashi Y, Kamiguchi K, Morimoto C (2000). "Beta 1-integrin-mediated cell signaling in T lymphocytes". J. Dermatol. Sci . 23 (2): 75–86. doi :10.1016/S0923-1811(99)00096-1 . PMID 10808124 . Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene . 138 (1–2): 171–4. doi :10.1016/0378-1119(94)90802-8 . PMID 8125298 . Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene . 200 (1–2): 149–56. doi :10.1016/S0378-1119(97)00411-3 . PMID 9373149 . Hattori A, Okumura K, Nagase T, et al. (2001). "Characterization of long cDNA clones from human adult spleen" . DNA Res . 7 (6): 357–66. doi :10.1093/dnares/7.6.357 PMID 11214971 . Terman JR, Mao T, Pasterkamp RJ, et al. (2002). "MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion" . Cell . 109 (7): 887–900. doi :10.1016/S0092-8674(02)00794-8 PMID 12110185 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Weide T, Teuber J, Bayer M, Barnekow A (2003). "MICAL-1 isoforms, novel rab1 interacting proteins". Biochem. Biophys. Res. Commun . 306 (1): 79–86. doi :10.1016/S0006-291X(03)00918-5 . PMID 12788069 . Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6" . Nature . 425 (6960): 805–11. Bibcode :2003Natur.425..805M . doi :10.1038/nature02055 PMID 14574404 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Fischer J, Weide T, Barnekow A (2005). "The MICAL proteins and rab1: a possible link to the cytoskeleton?". Biochem. Biophys. Res. Commun . 328 (2): 415–23. doi :10.1016/j.bbrc.2004.12.182 . PMID 15694364 . Bayer M, Fischer J, Kremerskothen J, et al. (2006). "Identification and characterization of Iporin as a novel interaction partner for rab1" . BMC Cell Biol . 6 (1): 15. doi :10.1186/1471-2121-6-15 PMC 1079803 PMID 15796781 . Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 PMID 17081983 . S2CID 7827573 . Jin X, Zhang J, Dai H, et al. (2007). "Investigation of the four cooperative unfolding units existing in the MICAL-1 CH domain". Biophys. Chem . 129 (2–3): 269–78. doi :10.1016/j.bpc.2007.06.008 . PMID 17662518 .
PDB gallery
1wyl : Solution structure of the CH domain of human NEDD9 interacting protein with calponin homology and LIM domains
2bra : STRUCTURE OF N-TERMINAL FAD BINDING MOTIF OF MOUSE MICAL
2bry : CRYSTAL STRUCTURE OF THE NATIVE MONOOXYGENASE DOMAIN OF MICAL AT 1.45 A RESOLUTION
2c4c : CRYSTAL STRUCTURE OF THE NADPH-TREATED MONOOXYGENASE DOMAIN OF MICAL
2co8 : Solution structures of the LIM domain of human NEDD9 interacting protein with calponin homology and LIM domains
2dk9 : Solution structure of Calponin Homology domain of Human MICAL-1
