His earliest definite work is the Mercy between Saint Martino and Catherine of Alexandria, painted for the monastery of Cimiez, near Nice, in 1475; recent historical searches have also suggested his having painted the Madonna of the Confraternity of the Misericordia at Nice in 1465. Other notable works by Brea can be found along all the coast from Monaco to Mentone, from Taggia to Imperia (where the influence of the Lombardy painter Vincenzo Foppa can be seen, and during which time he was in the service of Pope Julius II), and from Savona to Genoa, where he was active from 1483, leaving his work to the Church of the Consolation.
In Liguria, Ludovico's siblings Peter and Antonio Brea also operated as painters, as did Antonio's son, Francisco Brea (of whom details are only known for the period from 1512 to 1555).
