This is a list of notable buildings in St. John's, Newfoundland and Labrador, Canada.

• Johnson Geo Centre
• Railway Coastal Museum
• The Rooms

• Colonial Building
• Confederation Buildings
• Government House
• Supreme Court of Newfoundland and Labrador

• 351
• Fortis Building

• Bishops College (now defunct)
• Gonzaga High School
• Holy Heart of Mary High School
• Memorial University of Newfoundland
• Prince of Wales Collegiate
• Saint Bonaventure's College

• Basilica of St. John the Baptist
• Cathedral of St. John the Baptist
• George Street United Church
• Masjid-an-Noor
• St. John's Hindu Temple

• Bank of British North America Building
• Cabot Tower
• Masonic Temple
• Murray Premises

• Arts and Culture Centre
• Avalon Mall
• CFS St. John's
• The Fluvarium
• Hotel Newfoundland
• Memorial Stadium
• Mile One Centre
• St. John's Convention Centre

• Architecture of St. John's, Newfoundland and Labrador
• List of tallest buildings in St. John's, Newfoundland and Labrador