Texas Christian University has more than 90,000 living alumni.^[1] Following is a list of notable Texas Christian University alumni by profession.

• Glenda Green – artist; author of Love Without End, Jesus Speaks (1998)
• Mary McCleary – contemporary artist with works in numerous public collections

• Brian Alvey – co-founder of Weblogs, Inc.; serial entrepreneur
• Beverley Bass (BA '74) – former American Airlines pilot; first female American Airlines captain and captain of the first all-female commercial jet airliner crew^[2]
• Kyle Bass – Principal and founder of Hayman Capital Management
• John Davis – billionaire entrepreneur; 1-800-Flowers founder
• Kathryn Farmer – CEO and President of BNSF Railway since 2021. First woman CEO of a Class I railroad.
• Maciej Kranz – Cisco Systems Vice President of Innovation
• Robert J. McCann – CEO of UBS Group Americas (2011–present)

• James Cash Jr. – former chairman of Harvard MBA program; senior associate dean and chairman of HBS Publishing; on boards of GE and Microsoft
• Theresa A. Powell – vice president of academic affairs at Temple University; president of the National Association of Student Personnel Administrators^[3]
• Jim Ranchino – pollster, political consultant, and political scientist on the faculty of Ouachita Baptist University in Arkadelphia, Arkansas
• Elizabeth MacLeod Walls – 15th President of William Jewell College; 14th President of Washington & Jefferson College

• Norman Alden – actor with a fifty-year career in movies and television, mostly in voice roles and small parts
• Cecil Brower – Western swing pioneer
• Betty Buckley – Tony Award-winning actress best known for playing Grizabella in the musical Cats
• Corby Davidson (attended Aug 1988 thru May 1991, did not graduate) – Dallas/Fort Worth sports radio personality with The Ticket 1310am
• Cynthia Dobrinski – handbell composer and clinician^[4]
• Kelli Finglass – Dallas Cowboys Cheerleaders, director of the Dallas Cowboys Cheerleaders, television personality, television producer
• Frederic Forrest – actor
• Daniel Fredrick -- Broadway stage actor
• John Gilliland – radio broadcaster who created the Pop Chronicles music documentary^[5]
• Skip Hollandsworth – journalist; screenwriter; Executive Editor of Texas Monthly magazine
• Kristin Holt – television personality; former Dallas Cowboys cheerleader; finalist on the original American Idol
• Clyde Hurley – jazz trumpeter soloist in "In the Mood" by Glenn Miller Band
• Daniel Hunter – known for his music project, Analog Rebellion (formerly PlayRadioPlay!)
• Benton Jennings – actor with a career in theatre, movies, television, and commercials.
• James Kerwin – film and theater director
• Chris Klein – film actor, American Pie, We Were Soldiers Once, And Young, Rollerball
• John Knowles – guitarist
• William Lewis – opera singer
• Wendy Powell – voice actress
• Shelby Ringdahl -- actress and Miss Missouri winner
• Tudi Roche – actress
• Rod Roddy – former The Price Is Right announcer
• Bob Schieffer – journalist with CBS News since 1969 and host of Face the Nation
• Travis Schuldt – television actor on Passions, 10-8: Officers on Duty and Scrubs
• Sarah Rose Summers – Miss USA 2018
• Rob Thomas – writer, Veronica Mars and Rats Saw God
• Nina Vance – founder, Alley Theatre in Houston, Texas
• Stephanie Vander Werf – model, TV presenter and beauty pageant contestant; Miss Panama 2012; represented Panama at the Miss Universe 2012
• Shantel VanSanten – actress, One Tree Hill, Final Destination 4, You and I
• William Walker – Metropolitan Opera baritone
• Van Williams – television actor on Bourbon Street Beat, Surfside 6, and the Green Hornet
• Travis Willingham – voice actor
• Peggy Willis-Aarnio – ballet historian

• Tim Curry – district attorney for Tarrant County from 1972 until his death in 2009
• S. Maurice Hicks, Jr. – Chief Judge, United States District Court for the Western District of Louisiana
• Zuberi Williams – Associate Judge, Maryland District Court (2015 – present)^[6][7]

• Horace S. Carswell Jr. – recipient of the Congressional Medal of Honor
• Gordon R. England (MBA '75) – 71st & 73rd Secretary of the Navy; Deputy Secretary of Defense (2005–2009)

• Dan Boren – former U.S Representative from Oklahoma's 2nd congressional district
• Israel "Bo" Curtis – Louisiana politician, did graduate studies at TCU^[8]
• Wendy Davis – 2014 candidate for Texas Governor and former state senator in the Texas Senate
• Hou Chong-wen – Deputy Mayor of Chiayi City, Taiwan
• Eddie Bernice Johnson (B.S. 1967) – U.S. Representative, Texas 30th congressional district
• Kyle Kacal (Certificate in Ranch Management) – member of the Texas House of Representatives from College Station since 2013
• Lois Kolkhorst (Class of 1988) – member of the Texas Senate since 2014 and former member of the Texas House of Representatives
• Mike Lang – member of Texas House of Representatives since 2017
• Tommy Merritt – former member of Texas House of Representatives and candidate for Texas Department of Agriculture
• Winthrop Paul Rockefeller – former Lieutenant Governor of Arkansas from 1996 to 2006
• John Roger Williams – U.S. Representative and former Secretary of State of Texas
• Thomas Pressly - member of the Louisiana Senate since 2024 and former member of the Louisiana House of Representatives.^{[citation needed]}

• Scott Ankrom – former Dallas Cowboys wide receiver^[9]
• Jake Arrieta – MLB pitcher Baltimore Orioles (2010–13), Chicago Cubs (2013–2017), Philadelphia Phillies (2018–2020)
• Ronnie Baker – American sprinter
• Desmond Bane – NBA, selected 30th overall in the 2020 NBA draft, selected for Rising Stars Challenge at 2022 NBA All-Star Game
• Pat Batteaux – former NFL player
• Sammy Baugh – 1935 Heisman Trophy finalist; member of the Pro Football Hall of Fame^[10][11]
• Josh Boyce – Wide receiver, New England Patriots
• Scott Brooks – former NBA point guard and current Oklahoma City Thunder head coach; won Coach of the Year Award 2010
• Larry Brown – former cornerback for the Dallas Cowboys and Oakland Raiders, and Super Bowl XXX MVP^[12]
• David Caldwell – former nose tackle for the Green Bay Packers^[13]
• Tank Carder – 2011 Rose Bowl defensive MVP; linebacker for the Cleveland Browns^[14]
• Matt Carpenter – MLB All-Star for the St. Louis Cardinals
• Andrew Cashner – pitcher for the Miami Marlins
• Ron Clinkscale – Quarterback, Canadian Football League
• Bill Collins – Masters Athletics world record holder^[15]
• Roosevelt Collins – former NFL player
• Charles Coody – PGA golf professional, Class of 1960, Texas Sports Hall of Fame (2000)
• Norm Cox – former professional football player
• Édgar Crespo – Olympic swimmer from Panama
• Andy Dalton (class of 2010) – 2011 Rose Bowl offensive MVP; Pro Bowl quarterback for the Cincinnati Bengals^[16]
• Kenneth E. Davis – 1984 Heisman Trophy finalist; All-American running back^[17]
• Jamie Dixon – Current TCU men's basketball head coach, and former head coach for the University of Pittsburgh^[18]
• Josh Doctson – Wide receiver for the Minnesota Vikings
• Max Duggan -- quarterback for the Los Angeles Chargers
• Taylor Featherston – infielder for the Philadelphia Phillies
• Brandon Finnegan – pitcher for the Cincinnati Reds, formerly of the Kansas City Royals; became the first player to play in a College World Series and an MLB World Series in the same year^[19]
• Keith Flowers – former NFL player^[20]
• Bobby Jack Floyd – former fullback for the Green Bay Packers and Chicago Bears^[21]
• Larry Foyt – semi-retired NASCAR and IRL driver^[22]
• Jeff Gladney – Cornerback for the Minnesota Vikings and the Arizona Cardinals
• Clint Gresham – Long snapper for the Seattle Seahawks
• Phil Handler – former NFL football player and coach^[23]
• Tom Hoge – PGA golfer
• J. J. Henry – PGA golfer, member of the 2006 Ryder Cup team^[24]
• Bryan Holaday – catcher for the Boston Red Sox
• Jerry Hughes – Linebacker for the Buffalo Bills
• Sandora Irvin – former WNBA player, San Antonio Silver Stars^[25]
• Quentin Johnston -- wide receiver for the Los Angeles Chargers
• Jeremy Kerley – wide receiver for the San Francisco 49ers
• Harry Kinzy – former MLB pitcher^[26]
• Max Knake – former Arena Football League quarterback^[27]
• Jenny Lidback – former LPGA golfer^[28]
• Bob Lilly – former Dallas Cowboys defensive tackle; member of the Pro Football Hall of Fame^[10]
• Robert Lyles- NFL linebacker for Houston Oilers, Atlanta Falcons
• Stansly Maponga – Defensive end for the New York Giants
• George McLeod – former NBA player^[29]
• Guy Morriss – former NFL Pro Bowl center; former head football coach at Baylor University and University of Kentucky^[30]
• Lee Nailon – former NBA player^[31]
• Marshall Newhouse – Offensive tackle for the Oakland Raiders^[32]
• Jeff Newman – former MLB All Star player for the Boston Red Sox and Oakland Athletics^[33]
• Cameron Norrie – British tennis player
• Davey O'Brien – 1938 Heisman Trophy winner; won the Walter Camp and Maxwell Award the same year^[34]
• David Pate – 1991 Australian Open Men's Doubles Champion; runner-up of the 1991 US Open in Men's Doubles^{[citation needed]}
• Matt Purke – pitcher for the Chicago White Sox
• Mike Renfro – former NFL receiver for the Houston Oilers and the Dallas Cowboys^[35]
• Joe Robb – Defensive end, Philadelphia Eagles 1959–60, St Louis Cardinals 1961–67, Pro Bowl 1966, Detroit Lions 1968–71, & WFL 1972–74.
• Khadevis Robinson – USA Olympian in the 800 meter run; multiple USATF gold medalist; world record-breaker, running the fastest leg in the 4x800 in 2006^[36]
• Aaron Schobel – retired Pro Bowl defensive end with the NFL's Buffalo Bills^[37]
• Bo Schobel – former defensive end with the NFL's Arizona Cardinals^[38]
• Matt Schobel – former tight end with the NFL's Philadelphia Eagles^[39]
• Angela Stanford – professional golfer on the LPGA Tour^[40]
• Jim Swink – All-American running back; member of the College Football Hall of Fame; runner-up for the 1955 Heisman Trophy^[41]
• Kurt Thomas – former NBA player^[42]
• LaDainian Tomlinson – 2006 NFL MVP and 2000 Heisman Trophy finalist; San Diego Chargers 2001–09; New York Jets 2010–2011^[43]
• Gregg Troy – head coach of the University of Florida swimming and diving team^[44]
• Kris Tschetter – former professional golfer on the LPGA Tour^[45]
• Jason Tucker – former wide receiver for the Canadian Football League's Edmonton Eskimos; four-time All Star; 91st Grey Cup MVP^[46]
• Johnny Vaught – 1932 All-American guard for TCU; former head coach of the University of Mississippi; member of the College Football Hall of Fame
• Jason Verrett – Cornerback for the San Francisco 49ers
• Will Walls – former NFL football player^[47]
• Daryl Washington – Linebacker for the Arizona Cardinals
• Kenrich Williams – NBA basketball player for the Oklahoma City Thunder
• Malcolm Williams – Cornerback for the New England Patriots
• Jeff Zimmerman – former All-Star pitcher for the Texas Rangers^[48]

• Richard J. Allen – writer
• Sandra Brown – bestselling fiction author
• Dan Jenkins – bestselling author and Sports Illustrated writer
• Sue Monk Kidd – bestselling author of The Secret Life of Bees
• Robert W. Russell – pen name Nas'Naga (1941–2021), poet and novelist from Ohio^[49]
• Bud Shrake – sportswriter and author

• Carson Huey-You – youngest graduate in TCU history, Graduated with a Bachelor's Degree in physics at age 14.

• The Professor (Roy Hinkley) – character from the 1960s TV series Gilligan's Island has, among his six degrees, a Ph.D. from TCU^[50]
• Reverend Timothy Lovejoy – animated character from The Simpsons^[51]