He was also a top expert in the field of archaeometry. He pioneered high-precision methods of neutron activation analysis at the Lawrence Berkeley Laboratory in the US. Neutron activation analysis helps to determine the origin of ancient pottery and other artifacts through the analysis of the clay from which they were made. He was helped in the project by another noted scientist Frank Asaro. Second millennium BC pottery known as Cypriot Bichrome ware was one of the first archaeological projects that Perlman and Asaro undertook.
In 2006, Perlman's former student and collaborator Frank Asaro transferred archives of their work at Lawrence Berkeley National Laboratory to the University of Missouri Research Reactor Center with the request that they transcribe these data and share them with the scientific community. After more than a decade, a (nearly) comprehensive archive of the work of Asaro, Perlman, and Michel on the geochemistry of archaeological and geological samples was produced by Matthew T. Boulanger.[9] This archive was provided to the scientific community via the Digital Archaeological Record (tDAR). The knowledge and experiences gained through working with these records has been used to recommend best practices to modern laboratories producing similar data to ensure that they remain useful into the future.[9][10]