From 1990 to 1997, Iotova worked at Bulgarian National Television as a reporter, editor, director and presenter of news and current affairs programmes. She then worked as the director of the press service of the Bulgarian Socialist Party.[2]
In addition to her committee assignments, Iotova served as chairwoman of the parliament's delegation to the EU-Montenegro Stabilisation and Association Parliamentary Committee and as member of the delegation to the Parliamentary Assembly of the Mediterranean. She was also a member of the European Parliament Intergroup on Integrity (Transparency, Anti-Corruption and Organized Crime).[3]
Ahead of Bulgaria's 2016 presidential elections, Iotova was officially nominated as the Bulgarian Socialist Party's running mate for presidential candidate Rumen Radev. After her election to the Vice Presidency, she resigned her MEP seat.[citation needed]