The request to close Japanese harbours to Westerners was doomed as Yokohama was the key springboard for Western activity in Japan. The mission was a total failure. Nagaoki however was very impressed with the advancement of French civilization, and became very active in promoting the dispatch of embassies and students abroad, once he had returned to Japan. He was finally put under house arrest by the Bakufu.
Nagaoki brought many documents from France, related especially to physics, biology, manufacture, textiles and also fermentation technologies. He is considered as one of the fathers of the wine industry in Japan.