The House of Pignatelli is the name an old and prominent Neapolitan family of Italian nobility, clergy, men of arts and sciences, whose members occupied significant positions in 18th and 19th century. The family has been regionally prominent since the 13th century. Among various titles, they held the title of Prince of the Holy Roman Empire.^[1]

• Antonio Pignatelli, Pope Innocent XII (Spinazzola, 13 March 1615 - Rome, 27 September 1700)
• Domenico Pignatelli di Belmonte (November 19, 1730 – February 5, 1803)
• Ettore Pignatelli e Caraffa, 1st Duke of Monteleone (born Naples, died Palermo, Sicily, 1535)
• Faustina Pignatelli Carafa, princess di Colubrano (died Naples 1785) Italian scientist
• Francesco Pignatelli (February 6, 1652 – December 15, 1734) Italian cardinal
• Francesco Pignatelli (18th century) Vicar General of Naples under Ferdinand IV of Naples
• Gennaro Granito Pignatelli di Belmonte (April 10, 1851 – February 16, 1948)
• Giovanni Battista Pignatelli sixteenth-century Italian riding master
• Joaquín Atanasio Pignatelli de Aragón y Moncayo eighteenth-century Spanish noble and ambassador to France
• Luciana Pignatelli (1935-2008) Italian fashion icon