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The highway crosses the border with Moldova twice and west of the city of Reni it continues as Moldovan national road M3.[2] The highway also passes the Moldovan village Palanca, Ștefan Vodă where Ukraine has jurisdiction on the road.
The highway stretches through the historic and cultural region of Budzhak and ends at the "Reni" border checkpoint.
The section of M15 from Reni to Izmail was previously designated as P33. A portion of the highway Odesa–Reni between Reni and Orlivka follows the narrow strip of land that is between Lake Cahul and the Danube.
Route
This article contains a bulleted list or table of intersections which should be presented in a properly formatted junction table. Please consult this guideline for information on how to create one. Please improve this article if you can.(November 2021)