Halorubrum lacusprofundi

Halorubrum lacusprofundi
Scientific classification
Domain:
Archaea
Kingdom:
Euryarchaeota
Phylum:
Euryarchaeota
Class:
Halobacteria
Order:
Haloferacales
Family:
Halorubraceae
Genus:
Halorubrum
Species:
H. lacusprofundi

Franzmann et al. 1989[1]
Binomial name
Halorubrum lacusprofundi
Synonyms
  • Halobacterium lacusprofundi Franzmann et al. 1989[2]

Halorubrum lacusprofundi is a rod-shaped, halophilic Archaeon in the family of Halorubraceae. It was first isolated from Deep Lake in Antarctica in the 1980s.[3]

Genome

Several strains of H. lacusprofundi have been discovered. The genome sequencing of the strain ACAM 32 was completed in 2008. The organism's genome consists of two circular chromosomes and a single circular plasmid. Chromosome I contains 2,735,295 base pairs encoding 2,801 genes and chromosome II contains 525,943 base pairs encoding 522 genes. The single plasmid contains 431,338 base pairs encoding 402 genes.[4] At least one strain of H. lacusprofundi (R1S1) contains a plasmid (pR1SE) that enables horizontal gene transfer, which takes place via a mechanism that uses vesicle-enclosed virus-like particles.[5][6][7]

Research

Its β-galactosidase enzyme has been extensively studied to understand how proteins function in low-temperature, high-saline environments.[8][9]

References

  1. ^ Page Species: Halorubrum lacusprofundi on "LPSN - List of Prokaryotic names with Standing in Nomenclature". Deutsche Sammlung von Mikroorganismen und Zellkulturen. Retrieved 10 September 2022.
  2. ^ Page Taxonomy browser (Halorubrum lacusprofundi) on "NCBI". Retrieved 10 September 2022.
  3. ^ Franzmann PD, Stacklebrandt E, Sanderson K, Volkman JK, Camberon DE, Stevenson PL, McMeekin TA, Burton HR (1988). "Halobacterium lacusprofundii sp. nov., a halophilic bacterium isolated from Deep Lake, Antarctica". Systematic and Applied Microbiology. 11 (1): 20–27. doi:10.1016/S0723-2020(88)80044-4.
  4. ^ Anderson IJ, DasSarma P, Lucas S, Copeland A, Lapidus A, Del Rio T, Tice H, Dalin E, Bruce DC, Goodwin L, Pitluck S, Sims D, Brettin TS, Detter JC, Han CS, Larimer F, Hauser L, Land M, Ivanova N, Richardson P, Cavicchioli R, DasSarma S, Woese CR, Kyrpides (2016). "Complete genome sequence of the Antarctic Halorubrum lacusprofundi type strain ACAM 34". Standards in Genomic Sciences. 11 (1): 70. doi:10.1186/s40793-016-0194-2. PMC 5018182. PMID 27617060.
  5. ^ Erdmann S, Tschitschko B, Zhong L, Raftery MJ, Cavicchioli R (9 September 2017). "A plasmid from an Antarctic haloarchaeon uses specialized membrane vesicles to disseminate and infect plasmid-free cells". Nature Microbiology. 2 (10): 1446–1455. doi:10.1038/s41564-017-0009-2. PMID 28827601. S2CID 38729395.
  6. ^ Gophna U, Altman-Price N (8 September 2022). "Horizontal Gene Transfer in Archaea—From Mechanisms to Genome Evolution". Annual Review of Microbiology. 76 (1): 481–502. doi:10.1146/annurev-micro-040820-124627. ISSN 0066-4227.
  7. ^ Gebhard LJ, Vershinin Z, Alarcón-Schumacher T, Eichler J, Erdmann S (June 2023). "Influence of N-Glycosylation on Virus-Host Interactions in Halorubrum lacusprofundi". Viruses. 15 (7): 1469. doi:10.3390/v15071469. PMC 10384203. PMID 37515157.
  8. ^ Karan R, Capes MD, DasSarma P, DasSarma S (2013). "Cloning, Overexpression, Purification, and Characterization of a Polyextremophilic β-galactosidase From the Antarctic Haloarchaeon Halorubrum lacusprofundi". BMC Biotechnol. 13: 10.1186/1472-6750-13-3. doi:10.1186/1472-6750-13-3. PMC 3556326. PMID 23320757.
  9. ^ Laye VJ, Karan R, Kim JM, Pecher WT, DasSarma P, DasSarma S (2017). "Key amino acid residues conferring enhanced enzyme activity at cold temperatures in an Antarctic polyextremophilic β-galactosidase". PNAS. 114 (47): 12530–35. Bibcode:2017PNAS..11412530L. doi:10.1073/pnas.1711542114. PMC 5703305. PMID 29109294.


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