In 2016, Busick began his writing career by drafting the story for the thriller film Urge.[1] He transitioned to television by writing episodes of Stan Against Evil and Castle Rock.[2][3] In 2019, he began his series of collaborations with directors Matt Bettinelli-Olpin and Tyler Gillett by drafting the screenplay for the horror film Ready or Not.[4] In 2020, he continued his collaborations with Bettinelli-Olpin and Gillett with the upcoming horror film Reunion.[5] The following year, he gained notability from writing the script for the slasher revival film Scream.[6] In January 2022, he was hired to script the upcoming horror film Final Destination: Bloodlines.[7][8] In February 2022, he wrote the screenplay for Scream VI, a sequel to the 2022 Scream slasher revival.[9] In October 2024, he wrote a sequel to his 2019 film Ready or Not.[10]