The Gran Premio Nacional, or Argentine Derby,^[1] is a Group 1 flat horse race in Argentina open to three-year-olds run over a distance of 2,500 metres (1.6 mi) at Hipódromo Argentino de Palermo. It is the third race in the Argentinian Triple Crown and is one of the oldest and most influential races in Latin American racing.^[2]

The Gran Premio Nacional has been run at Hipódromo Argentino de Palermo annually since 1884.^[1]

By 1923, the year the Uruguayan entry Sisley won, the purse was worth $40,000.^[3]

In 1933, the favorite Hasta Hoy was attacked by masked men the night before the race.^[4] His attendant was held at gunpoint while Hasta Hoy's abdomen was stabbed. Hasta Hoy was left unable to run, leaving Requiebro and Támesis to dead heat for first in a field of ten, the smallest in the race up to that point.^[5]

In 2022, SIS (Sports Information Services) began sponsoring the race.^[6]

Speed record:

• 2:31.65 – Chullo (1997)

Largest margin of victory:

• 15 lengths – Great Escape (2020)

Longest odds winner:

• 107.10 – Priest (1992)

Shortest odds winner:

• 1.55 – Refinado Tom (1996)

Most wins by a jockey:

• 4 – Juan Carlos Noriega (1998, 2001, 2003, 2004)

Most wins by a trainer:

• 5 – Roberto Pellegatta (2001, 2003, 2004, 2005, 2023)
• 3 – Jorge A. Mayansky Neer (2013, 2017, 2020)

Most wins by an owner:

• 2 – F.F.C. (2001, 2004)
• 2 – Haras La Providencia (2002, 2015)
• 2 – S. de B. (2014, 2018)

Most wins by a breeder:

• 4 – Haras Abolengo (2010, 2013, 2020, 2023)
• 3 – Haras La Biznaga (1990, 1996, 2009)
• 2 – Haras La Quebrada (1993, 1994)
• 2 – Haras de la Pomme (1995, 2019)

ƒ designates a filly winner

ƒ indicates a filly

^[44]