Clough was born on 21 June 1991 in Sheffield, England.[1] She was born with Erb's palsy and had multiple operations to repair nerve damage in her shoulders shortly after birth. While at school, Clough began playing sports as a basketball player and captain in Yorkshire. She also played on a football team at the University of Leeds while completing a degree in sociology.[2] She continued her rowing career while studying at Kellogg College, Oxford.[3]
In the following years, Clough won an additional gold medal in mixed coxed four at the 2016 Summer Paralympics and the 2017 World Rowing Championships.[6] In 2018, Clough won gold at the 2018 World Rowing Championships in the mixed coxed four event.[7] After the event, Clough took a year off to heal from a pelvic injury.[8] In 2020, Clough planned to become a physical education teacher following her post-secondary studies. With her transition to teaching, Clough ended her rowing career.[9]