Glycopolymer

Glycopolymer is synthetic polymer with pendant carbohydrates.[1] Glycopolymers play an important role in many biological recognition events such as cell–cell adhesion, development of new tissues and infectious behavior of virus and bacteria. They have high potential in targeted drug delivery, tissue engineering and synthesis of bio-compatible materials.

The first glycopolymer was synthesized in 1978 by free-radical polymerization.[2] Subsequent efforts have been devoted to synthesizing glycopolymers with various structures and sizes, and the synthesis techniques have widened to controlled/living radical polymerisation, ring-opening polymerization, ring-opening metathesis polymerization and post-functionalization.[3]

References

  1. ^ S. Pearson, G. Chen, and M. H. Stenzel, Synthesis of Glycopolymers. Engineered Carbohydrate-Based Materials for Biomedical Applications. 2011: John Wiley & Sons, Inc. 1–118.
  2. ^ V. Horoejsí, O. Chaloupecká, and j. Kocourek, Studies on lectins: XLIII. Isolation and characterization of the lectin from restharrow boots (Ononis hircina Jacq.). Biochimica et Biophysica Acta (BBA) - General Subjects, 1978. 539(3): p. 287–293.
  3. ^ Aksakal, R.; Mertens, C.; Soete, M.; Badi, N.; Du Prez, F. (2021). "Applications of Discrete Synthetic Macromolecules in Life and Materials Science: Recent and Future Trends". Advanced Science. 2021 (2004038): 1–22. doi:10.1002/advs.202004038. PMC 7967060. PMID 33747749.

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