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His Eminence Giovanni Piccolomini
Dean of the College of Cardinals
Church	Roman Catholic Church
Appointed	26 February 1535
Term ended	21 November 1537
Predecessor	Alessandro Farnese
Successor	Giovanni Domenico de Cupis
Other post(s)	Apostolic Administrator of L'Aquila (1532-37) Cardinal-Bishop of Ostia-Velletri (1535-37)
Previous post(s)	Archbishop of Siena (1503-29) Commendatory Abbot of San Galgano (1516-22) Cardinal-Priest of Santa Sabina (1517-21) Cardinal-Priest of Santa Balbina (1521-24) Apostolic Administrator of L'Aquila (1523-25) Cardinal-Bishop of Albano (1524-31) Apostolic Administrator of Umbriatico (1524-31) Cardinal-Bishop of Palestrina (1531-33) Cardinal-Bishop of Porto e Santa Rufina (1533-35) Vice-Dean of the College of Cardinals (1533-35)
Orders
Created cardinal	1 July 1517 by Pope Leo X
Rank	Cardinal-Priest (1517-24) Cardinal-Bishop (1524-37)
Personal details
Born	Giovanni Piccolomini 9 October 1475 Siena, Republic of Siena
Died	21 November 1537(1537-11-21) (aged 62) Siena, Republic of Siena
Buried	Siena Cathedral
Parents	Andrea Todeschini Piccolomini Agnese Farnese
Coat of arms

Giovanni Piccolomini (1475–1537) was an Italian papal legate and cardinal. He was a nephew of Pope Pius III.

He was made Archbishop of Siena in 1503, Bishop of Sitten in 1522, Bishop of Aquila in 1523, Bishop of Albano in 1524, Bishop of Palestrina in 1531, Bishop of Porto e Santa Rufina in 1533, Bishop of Ostia in 1535.

He was made Dean of the College of Cardinals in October 1534.

• Miranda, Salvador. "PICCOLOMINI, Giovanni (1475-1537)". The Cardinals of the Holy Roman Church. Florida International University. OCLC 53276621. Retrieved 29 February 2016.