This implies that A is equivalent to the Serre quotient category of Mod-R by a certain localizing subcategoryC. (A localizing subcategory of Mod-R is a full subcategory C of Mod-R, closed under arbitrary direct sums, such that for any short exact sequence of modules , we have M2 in C if and only if M1 and M3 are in C. The Serre quotient of Mod-R by any localizing subcategory is a Grothendieck category.) We may take C to be the kernel of the left adjoint of the functor S.
Note that the embedding S of A into Mod-R is left-exact but not necessarily right-exact: cokernels of morphisms in A do not in general correspond to the cokernels of the corresponding morphisms in Mod-R.
References
Castaño Iglesias, Florencio; Enache, P.; Năstăsescu, Constantin; Torrecillas, Blas (2004), "Un analogue du théorème de Gabriel-Popescu et applications", Bulletin des Sciences Mathématiques, 128 (4): 323–332, doi:10.1016/j.bulsci.2003.12.004, ISSN0007-4497, MR2052174
Gabriel, Pierre; Popesco, Nicolae (1964), "Caractérisation des catégories abéliennes avec générateurs et limites inductives exactes", Les Comptes rendus de l'Académie des sciences, 258: 4188–4190, MR0166241 [Remark: "Popescu" is spelled "Popesco" in French.]