In 1907 he was married and, shortly after, became a professor at the Ghent Academy.[2] A few years later, his family life and artistic career were disturbed by a relationship with the actress Stella van de Wiele (1887–1954). In 1914, he gave up his position and spent six months in the United States.[1]
During World War I, Van den Berghe became a refugee in the Netherlands. He, Stella and De Smet toured the art colonies in Amsterdam, Blaricum and Laren, where he briefly taught.[2] His work also matured and came under the influence of Freudian psychoanalysis. In 1922, after returning to Belgium, he lived with De Smet and Permeke in Ostend. After that, he and De Smet moved about western Flanders, seeking inspiration, and finally settled in Afsnee at a villa supplied by Van Hecke.[1]
Van den Berghe later spent some time in Brussels, but the Great Depression virtually eliminated the market for any sort of modern art, so he returned to Ghent and became an illustrator for the Socialist newspaper, Vooruit [nl] (Forward).[1] He worked for them until his death. From 1937 to 1938, he drew the panels for a comic strip written by Jean Ray.[2] During his later years, he painted in a surrealistic style, replete with dream visions and hallucinations. He died in Ghent on 23 September 1939.
Major retrospectives were held in 1962 (Brussels) and 1984 (Utrecht). On the sixtieth anniversary of his death, in 1999, a large exhibition was held in Ostend with, for the first time, his illustrations. His painting, "Zondag" (Sunday), was included in the German series 1000 Meisterwerke and featured on a Belgian postage stamp in 2001.
Piet Boyens, Patrick Derom, Gilles Marquenie: Frits Van Den Berghe: Catalogue Raisonné, Exhibitions International, 2012 ISBN90-532-5136-7
Anne Marie Musschoot, Yves T'Sjoen, Joost De Geest: Frits Van den Berghe en Richard Minne. Stripverhalen 1931–1935, Snoeck-Ducaju & Zoon, 1996 ISBN90-506-6167-X
Emile Langui, Frits Van den Berghe 1883–1939. De mens en zijn werk, Mercatorfonds, Antwerp, 1968
Paul-Gustave Van Hecke, Frits Van den Berghe, Volume 9 of "Monographies de l'art belge: Série 2", De Sikkel, 1950