Agüero had a period in the youth of Sportivo Independiente, which preceded his move to Instituto.[3][4] His first club at senior level became Instituto in 2015.[1][5]Atlético Paraná were the opponents for Agüero's professional debut on 4 April 2015, with the defender playing the entirety of a 2–0 loss.[1] After making twenty-eight appearances for them, his first goal arrived in September 2016 against Estudiantes at the Estadio Presidente Perón.[1]