Epitizide
Epitizide
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Names
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Preferred IUPAC name
6-Chloro-1,1-dioxo-3-{[(2,2,2-trifluoroethyl)sulfanyl]methyl}-1,2,3,4-tetrahydro-1λ6,2,4-benzothiadiazine-7-sulfonamide
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Identifiers
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ChemSpider
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ECHA InfoCard
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100.015.620
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EC Number
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KEGG
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UNII
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InChI=1S/C10H11ClF3N3O4S3/c11-5-1-6-8(2-7(5)23(15,18)19)24(20,21)17-9(16-6)3-22-4-10(12,13)14/h1-2,9,16-17H,3-4H2,(H2,15,18,19) NKey: RINBGYCKMGDWPY-UHFFFAOYSA-N NInChI=1/C10H11ClF3N3O4S3/c11-5-1-6-8(2-7(5)23(15,18)19)24(20,21)17-9(16-6)3-22-4-10(12,13)14/h1-2,9,16-17H,3-4H2,(H2,15,18,19) Key: RINBGYCKMGDWPY-UHFFFAOYAQ
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C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)NC(N2)CSCC(F)(F)F
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Properties
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C10H11ClF3N3O4S3
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Molar mass
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425.85525
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Pharmacology
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C03EA03 (WHO) (combination with potassium-sparing diuretics)
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Epitizide is a diuretic. It is often combined with triamterene.[1]
References
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