The mammals are the class of vertebrate animals characterized by the presence of mammary glands, which in females produce milk for the nourishment of young; the presence of hair or fur; specialized teeth; the presence of a neocortex region in the brain; and endothermic or "warm-blooded" bodies. The brain regulates endothermic and circulatory system, including a four-chambered heart. Mammals encompass some 5,500 species (including Humans), distributed in about 1,200 genera, 152 families and up to 46 orders, though this varies with the classification scheme.