At Milwaukee, McCants led the Panthers to their first two Horizon League regular season championships in 2004 and 2005, earning first team all-conference honors both years. As a junior in 2003–04, McCants paired with Dylan Page to propel Milwaukee to a 20-11 record and a berth in the 2004 National Invitation Tournament. He averaged 17.1 points, 3.5 rebounds and 2.0 assists per game.
With the departure of Page the next season, McCants became the focal point of the offense. He responded by averaging 17.4 points per game and leading the Panthers to a 26-6 season and winning both regular season and conference tournament titles. Making the 2005 NCAA tournament, McCants led the 12 seed Panthers to a first round upset over fifth seeded Alabama. McCants scored 21 points in the 83-73 victory. In the second round, the Panthers knocked out 4 seed Boston College with McCants scoring 18, leading the program to its first Sweet 16 in its history.[2] At the close of the season, McCants was named Horizon LeaguePlayer of the Year and an Associated Press honorable mention All-American.[3]
Ed McCants Co-Founder of "Hidden Gems AAU Program" (2005, currently the active Vice President assists aspiring high school athletes prepare for college. Providing a structured summer workout coined "Summer is Serious" McCants aims to provide Marion, Ohio with an enhanced sense of tradition and pride for young hoopsters. Since the start of the "Hidden Gems" program has assisted more than 100 basketball players in landing college athletic scholarships. McCants has since begun expanding the "Hidden Gems" success into the Northwest Ohio area.