Duffy may refer to:

• Duffy (surname), people with the surname Duffy or Duffey
• Duffy (nickname)
• Duffy (singer) (born 1984), Welsh singer, born Aimee Ann Duffy

• Duffy, Australian Capital Territory, a suburb of Canberra
• Duffy, Ohio, United States, an unincorporated community
• Duffy, West Virginia, United States, an unincorporated community
• Duffy Fairgrounds, a stadium in New York, United States
• Duffy's Hill, a hill in Manhattan, New York
• Duffy's Peak, a hill or butte in Texas, United States
• Duffy Peak, a mountain on Alexander Island, Antarctica

• Duffy the Disney Bear, an anthropomorphic teddy bear character featured at Disney theme parks
• Duffy (film), a 1968 comedy starring James Coburn
• Duffy (novel), a 1980 novel by Julian Barnes writing as Dan Kavanagh
• Tristan Duffy, a fictional character in American Horror Story

• USS Duffy (DE-27), a US Navy destroyer

• Duffy antigen system, a type of cell marker proteins and the gene which codes for them
• Duffy site, an archaeological site in Illinois, United States
• Duffy Square, part of Times Square in New York City, United States
• Duffy & Snellgrove, an Australian book publishing company
• Duffey (disambiguation)
• Duffie, a surname
• Dufy, a surname
• O'Duffy, a surname

This disambiguation page lists articles associated with the title Duffy.
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