The history of Drohiczyn Land as a separate entity dates back to 1413, when it was part of Trakai Voivodeship of the Grand Duchy of Lithuania. In 1513, it made up the newly created Podlasie Voivodeship, together with two other lands: Bielsk Land and Mielnik Land. Local sejmiks took place at Drohiczyn, where two envoys to the WarsawSejm were elected.