In 1904, downtown Baltimore was almost destroyed by a huge fire with damages estimated at $150 million. Since the City of Baltimore was chartered in 1796, this downtown nucleus has been the focal point of business in the Baltimore metropolitan area. It has also increasingly become a heavily populated neighborhood with over 37,000 residents and new condominiums and apartment homes being built steadily.
Westside Baltimore is the western portion of downtown Baltimore that includes Market Center and many of the newest developments in downtown Baltimore, including the Baltimore Convention Center. It is also home to the site of the "Superblock" project that will include hundreds of condos and apartments as well as a variety of retail and commercial space. The former home of Baltimore's many and famed department stores, Westside Baltimore is now anchored by the University of Maryland, Baltimore consisting of the University of Maryland Health System, University of Maryland School of Law and the University of Maryland Biopark. The Westside is also home to several performing arts centers, including the Hippodrome Theatre, Royal Farms Arena, and the Everyman Theatre. G. Krug & Son Ironworks and Museum, in its original location, is the oldest continually operating blacksmith shop in the United States as well as a museum.
The former home of famed American writer Edgar Allan Poe is located at the Edgar Allan Poe House and Museum, a few blocks northwest from his grave at the intersection of Greene and Fayette streets. Nearby is the historic Lexington Market, one of the longest-running markets in the world, having been founded in 1782 and in continual operation since, selling a variety of prepared foods and groceries.
Mount Vernon, also known as the cultural district, is a high-density area just north of Downtown known for its attractive nightlife, buoyed by its large number of bars, clubs and lounges and its historic multi-story townhomes (most of which have been transformed into apartments) and traditional apartment buildings. Mount Vernon features the Joseph Meyerhoff Symphony Hall, home of the Baltimore Symphony Orchestra, as well as the Lyric Opera House. The world-renowned Peabody Institute is also located in Mount Vernon adjacent to the Walters Art Museum. To the very north is Penn Station, which offers Amtrak service to several U.S. major cities as well as MARC service to Washington, D.C. A major north–south avenue in Mount Vernon is Cathedral Street, named for the National Shrine of the Assumption, the first Catholic cathedral built in the United States, which is also considered the masterpiece of Benjamin Henry Latrobe, the "father of American architecture" and famed creator of the U.S. Capitol.
Downtown Baltimore offers many options for transportation, including subway, light rail, bus service, Amtrak, MARC Train service through Penn Station and Camden Station as well as access to I-83, I-695, I-95, 295, and 395.