Difetarsone

Difetarsone
Skeletal formula of difetarsone
Space-filling model of the difetarsone molecule
Clinical data
ATC code
Identifiers
  • [4-[2-[(4-arsonophenyl)amino]ethylamino]phenyl] arsonic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.020.788 Edit this at Wikidata
Chemical and physical data
FormulaC14H18As2N2O6
Molar mass460.149 g·mol−1

Difetarsone is an antiprotozoal agent. Various studies have shown it to be particularly effective against Trichuris trichiura, commonly known as the whipworm. Prior to the drugs use in the early 1970s, there were few effective treatments for this infection.[1] It has also been used to treat Entamoeba histolytica infections.[2]

Difetarsone often has minor side effects, which include rashes, nausea and vomiting. It has also resulted in angioedema in at least one known case.[2]

References

  1. ^ Leary PM, Jones C, Douglas F, Boyd ST (June 1974). "Difetarsone in outpatient treatment of Trichuris trichiura infestation". Archives of Disease in Childhood. 49 (6): 486–8. doi:10.1136/adc.49.6.486. PMC 1648795. PMID 4851370.
  2. ^ a b Aronson JK (2009). Meyler's Side Effects of Antimicrobial Drugs. p. 834. ISBN 9780080932934. Retrieved October 7, 2013.
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