Nikhil Sood is an overworked and underpaid police officer who gets a call on the emergency helpline number,100, one night. It is from a woman who is threatening to commit suicide. Nikhil says he needs her information in order to help her, but the woman refuses, saying she is going to die anyway.
Nikhil's wife Prerna calls to alert him that she thinks their son Dhruv could be back to his old habits of being a drug peddler. Dhruv leaves home late at night, at the same time Nikhil leaves for his late night shift. Nikhil rings his son and makes him return home. But before that, the mysterious woman threatening suicide reaches his house and holds Prerna captive. She forces Prerna to sit in her car and calls Nikhil, who realizes that she is Seema Palav. Seema's son died in a hit-and-run case; a rich spoilt brat Yash Mehra's car was the one that hit him. The case got shut down due to pressure from the city's hotshots and Seema thinks Dhruv had a hand in it. Her motive is revenge by killing Yash. She wants Dhruv to get Yash to her. Dhruv brings Yash for Seema; Nikhil also arrives.
Seema shoots both Yash and Dhruv, while Nikhil shoots Seema. Yash survives, but Dhruv is dead. In the end, similarly, Yash's parents are seen offering money to Nikhil to close the case. Nikhil returns to his control room to report the entire case, not falling for the money and the story ends.
Rahul Desai of Film Companion wrote, "Even though Dial 100 gets its nihilistic messaging on point, the gimmicky execution ensures the film is about as surprising as a traffic jam in Andheri East."[8]