Between Woodward Avenue and Bushwick Avenue, DeKalb Avenue is a two-way, two-lane street; between Bushwick Avenue and Fulton Street, it is one-way westbound. Lafayette Avenue is the corresponding parallel one-way street eastbound.
The B38 bus, operated by MTA New York City Transit, runs along the avenue west of Seneca Avenue. Ridgewood-bound buses run on Lafayette Avenue from Fulton Street to Broadway, then on Kossuth Place until Bushwick Avenue.