Raised in the Toronto suburb of Etobicoke, DeSanto made his acting debut at the age of 8 as the lead protagonist in Brown Bread Sandwiches (a.k.a. La famiglia Buonanotte), a film about Italian immigrants in Toronto written and directed by Carlo Liconti. Prior to his first screen role, DeSanto had been in a juice commercial with Canadian figure skating star Elizabeth Manley, and was an avid hockey player.[1][2] He later attended Martingrove Collegiate Institute and graduated in 1999.[citation needed] After attending MCI, he then attended Ryerson University for Film Studies.[3]