Keefe played in The Poor Nut on stage and was the only member of that cast to appear in the film adaptation.[3] After playing romantic leads in silent films, by 1941 Keef had changed to "a new career as a character actor".[4] He also acted on radio.[4]
In popular culture
Keefe was the focus of the Homer Hoopee comc strip on February 24, 1940. One of the female characters sought to get her husband to pay more attention to her by going out with Keefe, her old schoolmate who had become a film star.[5]