The club was founded by a group of young people in 1917, and its name was chosen to commemorate the first balloon flight across the Andes mountain, which had happened in 1916.
The third run in Primera División was in 2000–01 and lasted only one season: Los Andes finished 19th out of 20 teams and was relegated to Primera B Nacional with the worst points average in the division.
After some seasons in the lower divisions, in 2014 Los Andes returned to B Nacional after winning a championship of the Primera B Metropolitana, but be relegated in the 2018–19 season.
Current squad
As of 7 August 2022
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.