After graduating from college, Babineaux-Fontenot spent 13 years in executive roles at Walmart, including executive vice president of finance and treasurer, and held leadership positions at Adams and Reese, LLP, and PwC. She was also the assistant secretary for the state Office of Legal Affairs and administrative law judge for the Louisiana Department of Civil Service.[3] After undergoing treatment for her cancer in 2015, Babineaux-Fontenot left Walmart to "grant her the time to glean some insight on how to best use her voice to make a positive impact on the lives of other men and women with cancer."[4]
On March 10, 2024, the University of Notre Dame announced that Babineaux-Fontenot will receive the University's 2024 Laetare Medal, the oldest and most prestigious honor given to American Catholics, at Notre Dame’s 179th University Commencement Ceremony on May 19, 2024.[8]