Ciudad Miguel Alemán is located in the northwest of the state of Tamaulipas. Its municipality shares borders with both the U.S. state of Texas and the Mexican state of Nuevo León. Within Tamaulipas, the municipality is bordered by the municipality of Camargo to the east and the municipality of Mier to the west.[2] To the north it borders Starr County, Texas, and to the south the Municipalities of Los Aldamas and Doctor Coss in Nuevo León.
The town of San Pedro de Roma was among the first in the region, but it was not until 1927, when the international bridge was constructed, that the town gained an international significance, gaining itself the title of "city" and becoming the seat of a new municipality.[2]