Mayo was featured in vamp roles produced by Fox Film Corporation, Metro Pictures, World Film Corporation,
and Ivan Film Productions, Inc.[1] Mayo's motion picture career was launched when she won a New York Telegraph contest as the most beautiful girl in New York.[2]
International spy Dr. Karl Graves was arrested in Lima, Ohio, where he traveled after watching Mayo perform at the Empire Theater in New York City. Graves authored Revelations of the Kaiser's Personal Spy. Mayo was in Lima with her manager, Phil Selznik, when Graves was apprehended, stopping first in Bucyrus, Ohio, when she left New York.[5]
Portsmouth, Ohio was one of the thirty American cities Mayo toured in 1917. After the screening of one of her feature films, she discussed her movie career with the audience. A reception was held in the lobby of the Columbia Theater in Portsmouth.[1] Aside from promoting movies, Mayo utilized her tour to recruit troops for service in World War I and to sell Liberty Bonds. She was assigned to the recruiting department of the U.S. Navy. She received a solid gold medal representing the American flag from the hospital corps in recognition of her service to the government. Mayo was one of the first women of the stage to be awarded the right to wear the button of the Liberty Legion.[6]
Mayo plays the scatterbrained Mrs. Chadwick in The Hottentot (1922). One reviewer
complimented her acting as a "bright characterization".[7] In the 1923 feature The Shock, starring
Lon Chaney, Mayo was compared to Mary Alden in her rendition of Ann Cardington, queen of the underworld. The same year, she was also cast as a supporting player in Don't Marry for Money, along with
Edith Yorke and Charles Wellesley.[8][9]
Mayo was in the troupe of the Wilkes Stock Company in April 1929 at the Majestic Theater in Los Angeles, California. She joined Edward Everett Horton in a stage production of The Hottentot.[11]
Mayo enjoyed cooking chicken a la king, interior decorating, and reading classic novels by Balzac and Alexandre Dumas.[12]