Chlorodehydromethyltestosterone (CDMT; brand name Oral Turinabol), also known as 4-chloro-17β-hydroxy17α-methylandrosta-1,4-dien-3-one, is an anabolic–androgenic steroid (AAS). It is the 4-chloro-substituted derivative of metandienone (dehydromethyltestosterone).
CDMT was the first original product of Jenapharm, an East Germanpharmaceutical company. It was patented in 1961. The idea of combining the structures of 4-chlorotestosterone (clostebol) and metandienone originated with chemist Albert Stachowiak.[citation needed] At the time, this represented a unique dissociation of anabolic from androgenic effects after oral administration.[clarification needed][2] The product was introduced for clinical use in 1965 and remained in use until 1994, when production was discontinued.[citation needed]
CDMT was the key steroid administered to approximately ten thousand East German athletes as part of a secret doping program, known as State Plan Topic 14.25, often without them knowing the nature of the "vitamins" they were forced to take. The program remained in place from about 1968 until the collapse of the German Democratic Republic in 1989. In the 1990s, Franke and Berendonk examined GDR archives to elucidate the expansive scope of this operation, which had resulted in numerous medal wins and world-record performances.[3]
^Sobolevsky T, Rodchenkov G (2012). "Detection and mass spectrometric characterization of novel long-term dehydrochloromethyltestosterone metabolites in human urine". The Journal of Steroid Biochemistry and Molecular Biology. 128 (3–5): 121–7. doi:10.1016/j.jsbmb.2011.11.004. PMID22142641. S2CID42460280.
