Worsley was the son of Ralph Worsley, of The Platt, Rusholme and his wife Isabel Massy, daughter of Edward Massy of Manchester.[3] He was a parliamentary captain in Lancashire in 1644. By 1650 he was lieutenant colonel of a regiment raised in Lancashire for Cromwell. In 1651 he was employed in the reduction of the Isle of Man.
Worsley commanded the detachment used in the expulsion of the Long Parliament[4] in 1653 and took charge of the "bauble" when Cromwell ordered it to be removed.[3]
A branch of the Worsley family settled at Platt Hall, Lancashire, now in Fallowfield in the City of Manchester. The hall was bought by Ralph Worsley (1625) from the Platt family. Ralph Worsley's father, Charles, was the great-grandson of Sir Geoffrey Worsley of Boothes and a kinsman of the Worsleys of Worsley Hall (from whom derived the Worsleys of Appuldurcombe and of Hovingham).
The family of Charles Worsley remained at Platt Hall until 1906, when it was sold to the Manchester Corporation, the city then encroaching on its estate. Elizabeth Tindal-Carill-Worsley, who sold the estate, was the granddaughter of Francis Sacheverel Darwin, son of Erasmus Darwin. She married Nicolas Tindal of Aylesbury, a great-grandnephew of Sir Nicholas Conyngham Tindal, Lord Chief Justice of England from 1829 – 1843. Their grandson, Group Captain Nicolas Tindal-Carill-Worsley (known as Tindal), was a bomber pilot in the Second World War and a major instigator of the "Great Escape". His son, Charles Tindal, is the current representative of the family.[6][7]