Catawba is known as a rural enclave of the Roanoke Valley with its farms, bed and breakfasts, and the Homeplace Restaurant. The Catawba Hospital, a mental health facility operated by the Commonwealth of Virginia, is near Route 311[4] and traces its history back to a resort established in 1857 to take advantage of the believed healing properties of a sulfur and limestone spring. Route 311 intersects State Route 785, which connects to Blacksburg, and State Route 779, which connects to Daleville, in Catawba.
The Appalachian Trail passes through the Catawba area and provides access to three notable trail landmarks, Dragon's Tooth, McAfee Knob, and Tinker Cliffs. These three landmarks are referred to as the Triple Crown of hiking in Virginia, and experienced hikers can climb to all three overlooks in a 32 mile loop.[5] The Homeplace Restaurant was a popular eatery for through hikers on the trail before it closed in 2020.[6]